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This designation is allowed to use of research chemicals strictly for in vitro testing and laboratory experimentation only

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Tesofensine is generally contraindicated for patients with uncontrolled hypertension, a history of arrhythmias, or severe anxiety disorders

doi:10.1126/science.1258366 Essuman K, Summers DW, Sasaki Y, Mao X, DiAntonio A, Milbrandt J

TB-500 operates primarily through actin polymerization and cell migration signaling, without the angiogenic mechanism that defines research into this compound

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